Morphea simulating paucibacillary leprosy clinically and histopathologically

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Persistent reaction in paucibacillary leprosy: case reports.

Three patients of histopathologically confirmed borderline-tuberculoid leprosy showing no acid-fast bacilli and with lesions confined to the face, 2 on the cheek and 1 on the forehead, were given multidrug therapy as recommended by the WHO for paucibacillary cases. Within 3 months the lesions showed signs of upgrading (or reversal) reaction which was substantiated by histopathology. In 1 patien...

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Treatment of paucibacillary leprosy patients with dapsone and rifampicin.

Dapsone resistance is found worldwide (1,2) and resistance to other available drugs such as clofazamine (3) and rifampicin (4) also occurs. It is known that paucibacillary leprosy patients harbour <106 bacilli (5). However, the treatment of paucibacillary leprosy is of long duration. It is psychologically undesirable for a symptom-free, paucibacillary patient to receive therapy for a long perio...

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Post-operative mycotic endophthalmitis diagnosed clinically and verified histopathologically.

THE clinical and histopathological features of exogenous intra-ocular fungus infections have recently been the subject of a review (Fine and Zimmerman, 1959) based upon cases filed in the Registry of Ophthalmic Pathology, special attention being directed to those which appeared as complications of intraocular surgery. As a result there emerged a rather distinctive clinico-pathological picture: ...

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Diagnostic challenges of single plaque-like lesion paucibacillary leprosy

The diagnosis of single-lesion paucibacillary leprosy remains a challenge. Reviews by expert dermatopathologists and quantitative polymerase chain reaction (qPCR) results obtained from 66 single-plaque biopsy samples were compared. Histological findings were graded as high (HP), medium (MP) or low (LP) probability of leprosy or other dermatopathy (OD). Mycobacterium leprae-specific genes were d...

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MDT-MB therapy in paucibacillary leprosy: a clinicopathological assessment.

BACKGROUND The World Health Organization recommends treatment regimens for paucibacillary (PB) and multibacillary (MB) leprosy, which differ in their duration and components. Hence accurate classification of the disease is required. To overcome difficulties in classification Uniform Multi Drug Therapy (U-MDT) has been recommended. AIM To evaluate the benefit of adding clofazimine to paucibaci...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology

سال: 2013

ISSN: 0019-5154

DOI: 10.4103/0019-5154.105325